Sub-100 nm Chitosan-Triphosphate-DNA Nanoparticles for Delivery of DNA Vaccines
نویسندگان
چکیده
منابع مشابه
Chitosan nanoparticles for the intracellular delivery of triphosphate nucleotide analogues
Aim Nucleotide analogues such as Azidothymidine-triphosphate (AZT-TP), the active form of Zidovudine, display an important pharmacological activity for the treatment of HIV. The administration of these nucleotide analogues would bypass the intracellular phosphorylation which can be a metabolic bottleneck. This possibility is however limited by their instability in physiological conditions, and ...
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ژورنال
عنوان ژورنال: Proceedings
سال: 2020
ISSN: 2504-3900
DOI: 10.3390/iecp2020-08653